Job Opportunities
Join the Global Headquarters of one of the World's leading companies in HIV and infectious disease research, as
Director, Pharmacogenomics
Based - Belgium Generous basic salary plus bonus and benefits
You will join a team of senior scientists within the 'Viral Disease and Therapy Markers' Group. Within an organisation that has already shown a strong commitment to long-term investment in pharmacogenomic support to its drug development processes, your role will be pivotal to the identification and management of pharmacogenomics projects.
Concentrating on the handling of strategic and critical scientific issues, which surround the use of pharmacogenomics you will work within an International matrix management structure, and have regular and rewarding communication with senior colleagues, across a range of functions. As such, you will be working as part of the 'Early Development' team, which is responsible for deciding, which of the well-characterised compounds to bring through to clinical development.
This is a senior position, which features a high level of complex decision-making, which is critical for the success of the pipeline. It is demanding an individual, who has both an in-depth knowledge and awareness of how the pharmacogenomics field moves and possesses the 'vision' to shape the biomarker strategy.
You'll be prepared to make strategic recommendations, which go beyond your current experience. As a strong and clear communicator, you will discuss your decisions credibly with the highest levels within the organisation.
PhD, MD or DVM qualified, you will have a minimum of 10 years scientific experience gained within an industry or academic environment. An in-depth knowledge of pharmacogenomic research will be coupled with a proven capability in experimental molecular biology research.
If you are fluent in written and spoken English and feel that this opportunity would provide you with a new challenge, please telephone Andy Smith at RSA Search & Selection on +44 (0) 1707 259333 for a confidential discussion quoting reference number AS05832 or simply send your CV and a brief covering letter to 05832@TheRSAGroup.com
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Raritan, New Jersey
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Description:
The applicant will join a diverse team and contribute his/her expertise in genetics to designing and critically evaluating studies. The applicant will be responsible for scanning and interpreting the recent literature to identify variation in key genes and signaling pathways that may be involved in disease development and progression. Responsibilities also include designing and running DNA and RNA-based assays including multiplex PCR, genotyping, DNA sequencing and real-time PCR in a GLP-compliant environment. Experience in computer programming will facilitate bioinformatics analyses, automating processes and interfacing with instruments.
Qualifications:
Successful candidates will have a PhD with a research emphasis on population genetics, excellent molecular biology and troubleshooting skills and computer programming ability. Related postdoctoral experience preferred. Applied knowledge of sequence analysis and manipulation using molecular biology software is necessary. Deep understanding of genetic variation, solid scientific writing, oral communication and people skills are a must. Familiarity with lab automation is a plus.
To Apply:
As a valued team member, you’ll receive a competitive salary and great benefits including medical/dental, a 401(k), a pension plan and a comprehensive wellness program. If interested, please apply directly on-line at our web site www.jnj.com/careers noting Req. Code 0509817. The Johnson & Johnson Family of Companies has a strong commitment to diversity and welcomes applications for all individuals. EOE M/F/D/V
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Senior / Principal Scientist Pharmacogenomics
Raritan, New Jersey
Company Description:
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Posting Date: March 31, 2005
Position Description:
The applicant would report to the Pharmacogenomics Principal Scientist and will be responsible
1. to conduct biomarker-based translational clinical pharmacogenomic research to explain and forecast between-subject and between-population differences in proof-of-principle, drug efficacy and safety in various therapeutic areas including CNS, metabolic disorder, oncology;
2. to design, manage clinical pharmacogenomics projects and interpret data to reinforce credibility internally and externally
3. to identify and/or assist in external collaborations in defined therapeutic areas
4. to interact with clinical teams and other involved partners in discovery and clinical development, to explain data and the value of pharmacogenomics, assess clinical issues in compound development where pharmacogenomics might provide solutions, help establish the bridge between discovery and clinical work, design/write clinical pharmacogenomics protocols, and prepare reports, manuscripts and other documents.
Position Qualifications:
The applicant must be a clinical pharmacologist or pharmacogeneticist with a Pharm D, or Ph.D. or M.D., Ph.D. Good understanding of regulations, biostatistics, clinical PK and familiarity with bioiniformatics are a definitive asset. GLP/GCP/GMP training with a strong focus on special requirements of work within clinical trials is required. Very good communications skills and diplomacy are a must for this position since the department provides global support for clinical trials, and is positioned within the drug discovery division. Ability to work in a multifunctional team and in a highly complex and global environment according to highest ethical standards and J&J credo values is required. Strong working knowledge of genetics/genomics and the impact of genetic variation/expression profiling on disease progression, predisposition or therapy are needed.
To Apply:
Please apply directly on-line at our web site www.jnj.com/careers noting Req. Number 0503054. Johnson & Johnson has a strong commitment to diversity and welcomes applications for all individuals. EOE M/F/D/V
Head of Clinical Pharmacogenetics
MD or PhD with at least 5 years experience in Human Genetics. Exceptional degree of ingenuity, creativity, and resourcefulness. Demonstrated ability to conduct innovative and independent research and development projects. Proficiency with full range of techniques used in own field of work; ability to develop information which extends a given field and may lead to newly developed concepts, theories, and products. Ability to anticipate regulatory requirements and plan accordingly. Excellent understanding of the Drug Development Process. Excellent supervisory skills. Excellent written and verbal communication skills. Ability to effectively interact with all levels of management within Development Ability to effectively interact with Research management and Development senior management Ability to positively influence decision making processes. Proven work/business ethics. Lead the Clinical PharmacoGenetics Group. Design pharmacogenetic protocols together with the Clinical Teams. Liaise with Research Disease Area Heads for genetic markers of disease. Responsible for Preventive and Individualized Medicine concepts and strategy. Member of the BioMarker Development leadership team. Code #20313
Director of Marker Localization
A Ph.D. in biochemistry, molecular or cellular biology with additional training in genetics or microbiology. Strong scientific skills in histology, histochemistry and molecular biology and a sound understanding of role of biomarkers in the drug development process. Excellent theoretical and experimental background in molecular biology including genetics, PCR related techniques, RNAi, pharmacogenomics and pharmacogenetics. Strong experience working with nucleic acids, toxicological and biochemical databases. At least five years of cross functional management with demonstrated leadership of teams of scientific researchers. Code #20518
Both of the above positions are located in Novartis’ Cambridge, MA offices. Interested candidates should submit their resumes via the Novartis Pharmaceuticals website, http://www.novartis.com for further consideration. Please use the appropriate code number which is listed above at the completion of the position description.
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